One of the concerns I have is the cam selection. There really isn't any info out there on these engines, so the selection we made is really the proverbial 'shot in the dark'.
When I was on the salt, I was able to speak to several guys running vintage engines. The name Dema Elgin came up time and time again.I just had a long talk with Dema, about engine details, our goals for the engine, etc.
To make a long story short, we're going to ship the cam and a couple of lifters to Dema. He's going to plot it against his recommendation, and let us know where we are. I have another blank, so if it's needed, he'll grind us another cam.
Thinking out loud - throwing out a few thoughts - and, of course, it's easier spending your money than mine.
Stop me if I'm off the rails
Despite these great looking ports, it is an arduous flow path, both in and out of this monster. Flow testing the block would likely get you some additional info that your cam guy can use.
I'm looking at the firing order with respect to the exhaust opening and closing events (1 8 7 3 6 5 4 2), it looks like the 3&5 and the 6&4 could be a problem . . . Thinking overlap, your high pressure in the center shared exhaust port might not let you fully evacuate the 3 and 6 cylinders.
As the 3 exhaust is closing, the 3 intake is beginning to open. At about that same time, the 5 exhaust is opening, flooding the shared exhaust port, raising the pressure in the exhaust port and not permitting the # 3 chamber to completely evacuate - and possibly forcing some of the exhaust into the intake port of the number 3 cylinder (bigger valve, path of least resistance).
Some of the interaction might be able to be minimized by designing timing events into the cam that limit the duration that both the 3&5 and the 6&4 exhaust valves are open simultaneously.
I'd also be looking at anti-reversion valve designs, if possible.
I know you're supercharging this thing, and that negates some of the interaction.
By the way, Elgin makes some superior cams for the A-block, and I'm pretty certain he's familiar with some of the scatter pattern concepts.
Just riffing -
My 2 cents - worth about half that . . .
And I'm loving this build!