As a great example -- during the Top Speed Shootout Mike Cook will request wind readings from the various course watchers as a vehicle is being final-readied for a run. We'll hear speeds from the zero, the three, the tower, the lights (about the 5 1/2) and at least one more, maybe at the 7 or 8.
They are NEVER all the same -- in either velocity or direction. The direction might be most of the 360 degrees of a circle, in fact.
Therefore, especially if you're running a fast vehicle - it's wise to ask for a wind reading form the starter before making a run at any event. Informed might just be safer.