Highly oxygenated and non-oxygenated gasolines were compared on the dyno for several years. We spent a lot of time to select the optimum spark advance settings and jetting for each mixture. The oxygenated fuels provided no benefits. Is there a reason for this?
Well, I really don't know why you have seen that. But, this is what I really do know.
I often use my Nitrous Hayabusa for fuel test. It has a relatively low static compression, but has a LOT of engine modifications. I've tested the following VP fuels C12, C16, Q16, MRX02, MR12 over a couple days along with 89 octane pump (8% ethanol) and pump E85 (80% ethanol), PLUS Ignite Race Fuel 114 (90%) ethanol. For reference, the bike makes ~185 wHP on 89 Pump.
The non-oxygenated fuels produce less power while MR12 will pickup almost 10 wHP over pump with MRX02 in a close second. Ignite Race Fuel is also very close with a timing bump. Fueling has to be adjusted as much as +10% with oxygenated gasolines and while I did adjust timing, it really didn't make a HUGE difference except with Ignite. And of course the ethanol based fuels require about 30% more fuel.