To carry it to extremes;
A street roadster with a 200 inch wheel base and 10% set back means front spark plug is 20" behind front axle. Stock rear wheel location and maximum hood length put entire engine in front of the grille shell.
Similar problem with a 200" G/F roadster, 25% set back is 50", with a maximum body length of 143'/152" put the engine right about in the center of the grille shell.