Yes, you should be able to run C-16 (116 octane or higher if available) race gas very easily if the ECU has knock sensing/auto-retard at 12-15 psi boost levels.
If the ECU doesn't have Knock sensing then you will have to "tread lightly"... Start at 8-10 psi, 11:1 fuel ratio, and max boost only at high rpm and see what is what.
Methanol would provide a lot more cooling of the fuel-air mixture, the internal combustion chamber parts, and would yield 10%+ more HP at the crank,,,But it is a lot more trouble and work to swap from gasoline and tricky toget things just right. If you get it the least bit wrong, your pistons will fail...
Especially If you are running carbs, I'd use race gas to sort out the turbo system and swap over at later date to methanol,,,,,, one can of worms at a time is best...
Are you running SCTA , AMA, or both???
Smitty