No claims to expert knowledge on this, but a few I've had some involvement during kitting engines NOT designed for blowers. Maybe some clues for your planning, I hope.
- 1000cc blower on 3000-3400cc engines. Anything over 9psi was too much heat and detonaton at high rpm. Rotors grow and hit the housing on a long pull.
- 1000cc blower on 1800cc engine was pretty good for street but could make enough pressure to hurt bearings and break crankshaft bolts because the engine was notcapable of that power level.
- 2000cc blower on 4300cc engine ran best with restrictor plate between throttle body and blower inlet. No detonation problems. Without restrictor, piston life was "first pull". Best was about 8psi without blower air temp issues until restrictor used to control boost at highest blower speed.
- Well built 3700cc engine with low comp pistons, NASCAR heads, Chevy 2" Cariilo rods, ball bearing ball under each ARP head stud. 8 injectors (2 behind the throttle body). Maxed at 13.5 psi because the blower belt only gave about 45 seconds at 15psi so we slowed it down. This 2000cc blower is a pretty good match for that street engine. 400/400 power and torque and max engine speed 7800.
You may be in a similar situation, where the engine is not optimized for supercharging. 300cc blower on a 650cc at Bonneville may be spinning too hard. That is a quick way to get the rotors to grow into the case because the heated compressed air doesnt evacuate well when blower speed is too high and you get up against port pressure from not enough cam, valve, and port. I'd be tempted to use the 500, make some restrictor plates, and keep the blower speed off the top of the graph. You will get all the boost your drive ratio can provide until you get toward the danger area of the map. You can try different plates easily, but do it on the inlet side of the blower.
I am certain there are many, here, who know a lot more about blowers than I do. This is just the results of about 8 years involvement in those kits. In the end, slowing the blower down was always more tolerable for these stock engines, and that sounds like where you are going. If I could supercharge my 650, I'd love to use an r410 but they are a lot more money than a Social Security check!
OK...here come the slingshots and bows & arrows!