There is no reason to think that avgas burns slower. Aviation doesn't have the restrictions that automotive does.
There are any number of ways of getting higher octane numbers. The only reason for doing this is if you are having "knock" problems.
The other reason is horsepower. Horsepower and octane have very little to do with each other, unless knock limits what you can do.
E85 has an octane of about 100. If you are thinking about running avgas, why not just run racing fuel? Don't tell me cost is a factor? There are any number of "octane boosters" out there too.
As a side note, possession and use of leaded gasoline in a regular on-road vehicle now carries a maximum $10,000 fine in the United States.
I can't see any reason that mixing fuels would cause you a problem.
The basic chemistry is hydrogen and carbon. That's why we call them hydrocarbons. Different combinations make different gasolines and ethanols. The additives for anti-knock properties are either tetra-ethel lead, as in avgas, or oxygenates, mainly methanol-derived MTBE and ethanol-derived ETBE. Both hydrocarbons. There are other agents used in other countries.
More info here
http://www.landracing.com/forum/index.php/topic,2308.0.html